Identity
HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
C14orf172,GCD14,Gcd14p,TRM61,hTRM61
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 115708
HGNC: 23790
Ensembl: ENSG00000166166
Variants:
dbSNP: 115708
ClinVar: 115708
TCGA: ENSG00000166166
COSMIC: TRMT61A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166166 | ENST00000299202 | H0Y2Q1 |
| ENSG00000166166 | ENST00000389749 | Q96FX7 |
| ENSG00000166166 | ENST00000389749 | A0A024R6Q2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34728628 | 2021 | N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism. | 67 |
| 34728628 | 2021 | N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism. | 67 |
| 26234676 | 2016 | TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis. | 42 |
| 26234676 | 2016 | TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis. | 42 |
| 26470919 | 2015 | Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. | 27 |
| 26470919 | 2015 | Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. | 27 |
Citation
Dessen P
TRMT61A (tRNA methyltransferase 61A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75201/trmt61a-(trna-methyltransferase-61a)
