Identity
HGNC
LOCATION
3p25.2
LOCUSID
ALIAS
PCH2B,SEN2,SEN2L
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80746
MIM: 608753
HGNC: 28422
Ensembl: ENSG00000154743
Variants:
dbSNP: 80746
ClinVar: 80746
TCGA: ENSG00000154743
COSMIC: TSEN2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA processing in the nucleus | REACTOME | R-HSA-6784531 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34964109 | 2022 | A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. | 3 |
| 34964109 | 2022 | A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. | 3 |
Citation
Dessen P
TSEN2 (tRNA splicing endonuclease subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75222/tsen2-(trna-splicing-endonuclease-subunit-2)
