Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7265
MIM: 601963
HGNC: 12391
Ensembl: ENSG00000113312
Variants:
dbSNP: 7265
ClinVar: 7265
TCGA: ENSG00000113312
COSMIC: TTC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113312 | ENST00000231238 | Q99614 |
| ENSG00000113312 | ENST00000518560 | H0YB37 |
| ENSG00000113312 | ENST00000522793 | Q99614 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 22711498 | 2012 | Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1. | 11 |
| 23067341 | 2012 | Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint). | 13 |
| 22711498 | 2012 | Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1. | 11 |
| 23067341 | 2012 | Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint). | 13 |
| 21486497 | 2011 | Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. | 3 |
| 21486497 | 2011 | Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. | 3 |
| 12748287 | 2003 | Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. | 18 |
| 14503850 | 2003 | Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation. | 7 |
| 12748287 | 2003 | Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. | 18 |
| 14503850 | 2003 | Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation. | 7 |
Citation
Dessen P
TTC1 (tetratricopeptide repeat domain 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75267/ttc1-(tetratricopeptide-repeat-domain-1)
