Identity
HGNC
LOCATION
21q22.13
LOCUSID
ALIAS
DCRR1,RNF105,TPRDIII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7267
MIM: 602259
HGNC: 12393
Ensembl: ENSG00000182670
Variants:
dbSNP: 7267
ClinVar: 7267
TCGA: ENSG00000182670
COSMIC: TTC3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37677864 | 2023 | An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. | 0 |
| 37677864 | 2023 | An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. | 0 |
| 33638766 | 2022 | TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment. | 8 |
| 33638766 | 2022 | TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment. | 8 |
| 33626494 | 2021 | Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene. | 5 |
| 33626494 | 2021 | Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene. | 5 |
| 30203323 | 2019 | Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus. | 4 |
| 30696809 | 2019 | TTC3 contributes to TGF-β(1)-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation. | 19 |
| 30203323 | 2019 | Overexpressed TTC3 Protein Tends to be Cleaved into Fragments and Form Aggregates in the Nucleus. | 4 |
| 30696809 | 2019 | TTC3 contributes to TGF-β(1)-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation. | 19 |
| 27586445 | 2016 | An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome. | 32 |
| 27586445 | 2016 | An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome. | 32 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20059950 | 2009 | The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt. | 75 |
Citation
Dessen P
TTC3 (tetratricopeptide repeat domain 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75282/ttc3-(tetratricopeptide-repeat-domain-3)
