Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80727
MIM: 608919
HGNC: 22222
Ensembl: ENSG00000136295
Variants:
dbSNP: 80727
ClinVar: 80727
TCGA: ENSG00000136295
COSMIC: TTYH3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Stimuli-sensing channels | REACTOME | R-HSA-2672351 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38908074 | 2024 | TTYH3 promotes the malignant progression of oral squamous cell carcinoma SCC-9 cells by regulating tumor-associated macrophage polarization. | 0 |
| 38908074 | 2024 | TTYH3 promotes the malignant progression of oral squamous cell carcinoma SCC-9 cells by regulating tumor-associated macrophage polarization. | 0 |
| 35844789 | 2022 | The TTYH3/MK5 Positive Feedback Loop regulates Tumor Progression via GSK3-β/β-catenin signaling in HCC. | 4 |
| 36142409 | 2022 | TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway. | 7 |
| 35844789 | 2022 | The TTYH3/MK5 Positive Feedback Loop regulates Tumor Progression via GSK3-β/β-catenin signaling in HCC. | 4 |
| 36142409 | 2022 | TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway. | 7 |
| 34385445 | 2021 | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. | 10 |
| 34796468 | 2021 | Upregulation of TTYH3 promotes epithelial-to-mesenchymal transition through Wnt/β-catenin signaling and inhibits apoptosis in cholangiocarcinoma. | 20 |
| 34385445 | 2021 | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. | 10 |
| 34796468 | 2021 | Upregulation of TTYH3 promotes epithelial-to-mesenchymal transition through Wnt/β-catenin signaling and inhibits apoptosis in cholangiocarcinoma. | 20 |
| 31558800 | 2020 | Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains. | 10 |
| 31558800 | 2020 | Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains. | 10 |
| 18577513 | 2008 | The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. | 14 |
| 18577513 | 2008 | The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. | 14 |
Citation
Dessen P
TTYH3 (tweety family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75356/teaching-explorer/tumors-explorer/
