TULP1 (TUB like protein 1)

2014-11-01  

Identity

HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
LCA15,RP14,TUBL1

Other Information

Locus ID:

NCBI: 7287
MIM: 602280
HGNC: 12423
Ensembl: ENSG00000112041

Variants:

dbSNP: 7287
ClinVar: 7287
TCGA: ENSG00000112041
COSMIC: TULP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112041ENST00000229771O00294
ENSG00000112041ENST00000322263O00294
ENSG00000112041ENST00000428978Q5TGM7
ENSG00000112041ENST00000614066A0A087WT25

Expression (GTEx)

0
1
2

References

Pubmed IDYearTitleCitations
361288532023Natural history and biomarkers of retinal dystrophy caused by the biallelic TULP1 variant c.148delG.2
361288532023Natural history and biomarkers of retinal dystrophy caused by the biallelic TULP1 variant c.148delG.2
348656122022TULP1 related retinal dystrophy: report of rare and novel variants with a previously undescribed phenotype in two cases.4
348656122022TULP1 related retinal dystrophy: report of rare and novel variants with a previously undescribed phenotype in two cases.4
339073722021A novel homozygous missense mutation p.P388S in TULP1 causes protein instability and retinitis pigmentosa.8
339073722021A novel homozygous missense mutation p.P388S in TULP1 causes protein instability and retinitis pigmentosa.8
264274152016TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR).5
269870712016Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.14
274409972016Pathogenic mutations in TULP1 responsible for retinitis pigmentosa identified in consanguineous familial cases.10
264274152016TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR).5
269870712016Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.14
274409972016Pathogenic mutations in TULP1 responsible for retinitis pigmentosa identified in consanguineous familial cases.10
245479282015Advantage of Whole Exome Sequencing over Allele-Specific and Targeted Segment Sequencing in Detection of Novel TULP1 Mutation in Leber Congenital Amaurosis.9
253422762015A TULP1 founder mutation, p.Gln301*, underlies a recognisable congenital rod-cone dystrophy phenotype on the Arabian Peninsula.7
245479282015Advantage of Whole Exome Sequencing over Allele-Specific and Targeted Segment Sequencing in Detection of Novel TULP1 Mutation in Leber Congenital Amaurosis.9

Citation

Dessen P

TULP1 (TUB like protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75377/tulp1-(tub-like-protein-1)