TYW5 (tRNA-yW synthesizing protein 5)

2014-11-01  

Identity

HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
C2orf60,hTYW5

Other Information

Locus ID:

NCBI: 129450
HGNC: 26754
Ensembl: ENSG00000162971

Variants:

dbSNP: 129450
ClinVar: 129450
TCGA: ENSG00000162971
COSMIC: TYW5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162971ENST00000354611A2RUC4
ENSG00000162971ENST00000441832A8KAJ9
ENSG00000162971ENST00000483328A8KAJ9

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
tRNA processingREACTOMER-HSA-72306
tRNA modification in the nucleus and cytosolREACTOMER-HSA-6782315
Synthesis of wybutosine at G37 of tRNA(Phe)REACTOMER-HSA-6782861

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345818042022Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.2
355272732022Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene.4
345818042022Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.2
355272732022Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene.4

Citation

Dessen P

TYW5 (tRNA-yW synthesizing protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75398/tyw5-(trna-yw-synthesizing-protein-5)