U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4)

2014-11-01  

Identity

HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
U2AF1-RS3,U2AF1L3,U2AF1L3V1,U2AF1RS3,U2af26

Other Information

Locus ID:

NCBI: 199746
MIM: 601080
HGNC: 23020
Ensembl: ENSG00000161265

Variants:

dbSNP: 199746
ClinVar: 199746
TCGA: ENSG00000161265
COSMIC: U2AF1L4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161265ENST00000292879Q8WU68
ENSG00000161265ENST00000378975Q8WU68
ENSG00000161265ENST00000412391Q8WU68
ENSG00000161265ENST00000587886A0A1D5RMU4
ENSG00000161265ENST00000587987K7EJH3
ENSG00000161265ENST00000589429S4R353
ENSG00000161265ENST00000591057K7EJM7
ENSG00000161265ENST00000591084S4R443
ENSG00000161265ENST00000594792M0R1E1
ENSG00000161265ENST00000600296S4R3L8
ENSG00000161265ENST00000601236M0QYK5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
ShigellosisKEGGhsa05131
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
321161232020The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.4
321161232020The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.4
271433772016[Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].0
271433772016[Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].0
232466982013Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.8
232466982013Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.8
220229692011Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.0
220229692011Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.0
184604682008Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.6
184604682008Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.6

Citation

Dessen P

U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75399/u2af1l4-(u2-small-nuclear-rna-auxiliary-factor-1-like-4)