Identity
HGNC
LOCATION
4q13.2
LOCUSID
ALIAS
E1-L2,MOP-4,UBE1L2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55236
MIM: 611361
HGNC: 25581
Ensembl: ENSG00000033178
Variants:
dbSNP: 55236
ClinVar: 55236
TCGA: ENSG00000033178
COSMIC: UBA6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38474091 | 2024 | UBA6 Inhibition Accelerates Lysosomal TRPML1 Depletion and Exosomal Secretion in Lung Cancer Cells. | 0 |
| 38474091 | 2024 | UBA6 Inhibition Accelerates Lysosomal TRPML1 Depletion and Exosomal Secretion in Lung Cancer Cells. | 0 |
| 34320783 | 2022 | UBA6 and NDFIP1 regulate the degradation of ferroportin. | 6 |
| 34320783 | 2022 | UBA6 and NDFIP1 regulate the degradation of ferroportin. | 6 |
| 32315024 | 2020 | Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5. | 5 |
| 32497710 | 2020 | Down-regulation of UBA6 exacerbates brain injury by inhibiting the activation of Notch signaling pathway to promote cerebral cell apoptosis in rat acute cerebral infarction model. | 3 |
| 32315024 | 2020 | Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5. | 5 |
| 32497710 | 2020 | Down-regulation of UBA6 exacerbates brain injury by inhibiting the activation of Notch signaling pathway to promote cerebral cell apoptosis in rat acute cerebral infarction model. | 3 |
| 31692446 | 2019 | Negative regulation of autophagy by UBA6-BIRC6-mediated ubiquitination of LC3. | 39 |
| 31692446 | 2019 | Negative regulation of autophagy by UBA6-BIRC6-mediated ubiquitination of LC3. | 39 |
| 28134249 | 2017 | Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes. | 23 |
| 28134249 | 2017 | Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes. | 23 |
| 27569286 | 2016 | LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6. | 6 |
| 27569286 | 2016 | LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6. | 6 |
| 26284580 | 2015 | Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder. | 6 |
Citation
Dessen P
UBA6 (ubiquitin like modifier activating enzyme 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75403/uba6-(ubiquitin-like-modifier-activating-enzyme-6)
