Identity
HGNC
LOCATION
11q12.3
LOCUSID
ALIAS
2B28,SAKS1,UBXD10
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51035
MIM: 616378
HGNC: 18402
Ensembl: ENSG00000162191
Variants:
dbSNP: 51035
ClinVar: 51035
TCGA: ENSG00000162191
COSMIC: UBXN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38773518 | 2024 | UBXN1 promotes liver tumorigenesis by regulating mitochondrial homeostasis. | 0 |
| 38773518 | 2024 | UBXN1 promotes liver tumorigenesis by regulating mitochondrial homeostasis. | 0 |
| 33754075 | 2021 | LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis. | 30 |
| 34246306 | 2021 | YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m(6)A modification to activate NF-κB and promote the malignant progression of glioma. | 69 |
| 33754075 | 2021 | LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis. | 30 |
| 34246306 | 2021 | YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m(6)A modification to activate NF-κB and promote the malignant progression of glioma. | 69 |
| 29685906 | 2018 | The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex. | 17 |
| 29685906 | 2018 | The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex. | 17 |
| 27785701 | 2017 | The opposite role of two UBA-UBX containing proteins, p47 and SAKS1 in the degradation of a single ERAD substrate, α-TCR. | 7 |
| 28152074 | 2017 | Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. | 17 |
| 27785701 | 2017 | The opposite role of two UBA-UBX containing proteins, p47 and SAKS1 in the degradation of a single ERAD substrate, α-TCR. | 7 |
| 28152074 | 2017 | Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. | 17 |
| 25681446 | 2015 | Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. | 21 |
| 25681446 | 2015 | Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. | 21 |
| 23545497 | 2013 | UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS. | 48 |
Citation
Dessen P
UBXN1 (UBX domain protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75445/ubxn1-(ubx-domain-protein-1)
