Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
UBXD1,UBXDC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80700
MIM: 611946
HGNC: 14928
Ensembl: ENSG00000167671
Variants:
dbSNP: 80700
ClinVar: 80700
TCGA: ENSG00000167671
COSMIC: UBXN6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34021047 | 2021 | UBX Domain Protein 6 Positively Regulates JAK-STAT1/2 Signaling. | 7 |
| 34021047 | 2021 | UBX Domain Protein 6 Positively Regulates JAK-STAT1/2 Signaling. | 7 |
| 31158522 | 2020 | Association of a single nucleotide polymorphism in the ubxn6 gene with long-term non-progression phenotype in HIV-positive individuals. | 3 |
| 31158522 | 2020 | Association of a single nucleotide polymorphism in the ubxn6 gene with long-term non-progression phenotype in HIV-positive individuals. | 3 |
| 31847414 | 2019 | Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase. | 6 |
| 31847414 | 2019 | Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase. | 6 |
| 30120381 | 2018 | UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy. | 25 |
| 30120381 | 2018 | UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy. | 25 |
| 27753622 | 2017 | VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy. | 167 |
| 27913212 | 2017 | VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease. | 23 |
| 27753622 | 2017 | VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy. | 167 |
| 27913212 | 2017 | VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease. | 23 |
| 26475856 | 2015 | The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97. | 20 |
| 26475856 | 2015 | The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97. | 20 |
| 23335559 | 2013 | Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase. | 32 |
Citation
Dessen P
UBXN6 (UBX domain protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75450/ubxn6-(ubx-domain-protein-6)
