UBXN7 (UBX domain protein 7)

2014-11-01  

Identity

HGNC
LOCATION
3q29
LOCUSID
ALIAS
UBXD7
FUSION GENES

Other Information

Locus ID:

NCBI: 26043
MIM: 616379
HGNC: 29119
Ensembl: ENSG00000163960

Variants:

dbSNP: 26043
ClinVar: 26043
TCGA: ENSG00000163960
COSMIC: UBXN7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163960ENST00000296328O94888
ENSG00000163960ENST00000381887H7BYF4
ENSG00000163960ENST00000413584C9JD50
ENSG00000163960ENST00000428095C9JAT7
ENSG00000163960ENST00000429160F8WB69

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360964512023HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.3
377443302023CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease.2
360964512023HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.3
377443302023CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease.2
362575782022CircUBXN7 suppresses cell proliferation and facilitates cell apoptosis in lipopolysaccharide-induced cell injury by sponging miR-622 and regulating the IL6ST/JAK1/STAT3 axis.2
362575782022CircUBXN7 suppresses cell proliferation and facilitates cell apoptosis in lipopolysaccharide-induced cell injury by sponging miR-622 and regulating the IL6ST/JAK1/STAT3 axis.2
334446482021UBXN7 cofactor of CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins.9
334446482021UBXN7 cofactor of CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins.9
325360592020[Circular RNA-UBXN7 promotes proliferation, migration and suppresses apoptosis in hepatocellular cancer].1
325360592020[Circular RNA-UBXN7 promotes proliferation, migration and suppresses apoptosis in hepatocellular cancer].1
282748782017Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase.8
282748782017Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase.8
225373862012UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.40
225373862012UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.40
216458542011Hierarchical binding of cofactors to the AAA ATPase p97.63

Citation

Dessen P

UBXN7 (UBX domain protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75451/ubxn7-(ubx-domain-protein-7)