Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7350
MIM: 113730
HGNC: 12517
Ensembl: ENSG00000109424
Variants:
dbSNP: 7350
ClinVar: 7350
TCGA: ENSG00000109424
COSMIC: UCP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000109424 | ENST00000262999 | P25874 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38917410 | 2024 | UCP1 expression in human brown adipose tissue is inversely associated with cardiometabolic risk factors. | 0 |
| 38917410 | 2024 | UCP1 expression in human brown adipose tissue is inversely associated with cardiometabolic risk factors. | 0 |
| 36651711 | 2023 | Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease. | 2 |
| 37256948 | 2023 | Structural basis of purine nucleotide inhibition of human uncoupling protein 1. | 8 |
| 37336486 | 2023 | Structural basis for the binding of DNP and purine nucleotides onto UCP1. | 8 |
| 38069028 | 2023 | Loss of Uncoupling Protein 1 Expression in the Subcutaneous Adipose Tissue Predicts Childhood Obesity. | 2 |
| 36651711 | 2023 | Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease. | 2 |
| 37256948 | 2023 | Structural basis of purine nucleotide inhibition of human uncoupling protein 1. | 8 |
| 37336486 | 2023 | Structural basis for the binding of DNP and purine nucleotides onto UCP1. | 8 |
| 38069028 | 2023 | Loss of Uncoupling Protein 1 Expression in the Subcutaneous Adipose Tissue Predicts Childhood Obesity. | 2 |
| 35090503 | 2022 | UCP1 modulates immune infiltration level and survival outcome in ovarian cancer patients. | 3 |
| 35541900 | 2022 | Mitochondrial Protein UCP1 Inhibits the Malignant Behaviors of Triple-negative Breast Cancer through Activation of Mitophagy and Pyroptosis. | 9 |
| 35598846 | 2022 | Inhibition of STAT3 enhances UCP1 expression and mitochondrial function in brown adipocytes. | 0 |
| 35691529 | 2022 | Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis. | 3 |
| 35805122 | 2022 | Chronic Fatty Acid Depletion Induces Uncoupling Protein 1 (UCP1) Expression to Coordinate Mitochondrial Inducible Proton Leak in a Human-Brown-Adipocyte Model. | 3 |
Citation
Dessen P
UCP1 (uncoupling protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75459/ucp1-(uncoupling-protein-1)
