UGT2A2 (UDP glucuronosyltransferase family 2 member A2)

2014-11-01  

Identity

HGNC
UGT2A2
LOCATION
4q13.3
LOCUSID
574537
ALIAS
UDPGT 2A2

Other Information

Locus ID:

NCBI: 574537
HGNC: 28183
Ensembl: ENSG00000271271

Variants:

dbSNP: 574537
ClinVar: 574537
TCGA: ENSG00000271271
COSMIC: UGT2A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000271271ENST00000604021Q9Y4X1
ENSG00000271271ENST00000604629Q9Y4X1

Pathways

PathwaySourceExternal ID
Pentose and glucuronate interconversionsKEGGko00040
Ascorbate and aldarate metabolismKEGGko00053
Steroid hormone biosynthesisKEGGko00140
Retinol metabolismKEGGko00830
Porphyrin and chlorophyll metabolismKEGGko00860
Metabolism of xenobiotics by cytochrome P450KEGGko00980
Drug metabolism - cytochrome P450KEGGko00982
Drug metabolism - other enzymesKEGGko00983
Pentose and glucuronate interconversionsKEGGhsa00040
Ascorbate and aldarate metabolismKEGGhsa00053
Steroid hormone biosynthesisKEGGhsa00140
Retinol metabolismKEGGhsa00830
Porphyrin and chlorophyll metabolismKEGGhsa00860
Metabolism of xenobiotics by cytochrome P450KEGGhsa00980
Drug metabolism - cytochrome P450KEGGhsa00982
Drug metabolism - other enzymesKEGGhsa00983
Metabolic pathwaysKEGGhsa01100
Glucuronate pathway (uronate pathway)KEGGM00014
Chemical carcinogenesisKEGGhsa05204
Chemical carcinogenesisKEGGko05204
Glucuronate pathway (uronate pathway)KEGGhsa_M00014
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
GlucuronidationREACTOMER-HSA-156588

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
350396402022The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.60
350396402022The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.60
198587812009Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.20
198587812009Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.20

Citation

Dessen P

UGT2A2 (UDP glucuronosyltransferase family 2 member A2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75470/ugt2a2-(udp-glucuronosyltransferase-family-2-member-a2)