UNC45B (unc-45 myosin chaperone B)

2014-11-01  

Identity

HGNC
UNC45B
LOCATION
17q12
LOCUSID
146862
ALIAS
CMYA4,CTRCT43,MFM11,SMUNC45,UNC-45B,UNC45
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 146862
MIM: 611220
HGNC: 14304
Ensembl: ENSG00000141161

Variants:

dbSNP: 146862
ClinVar: 146862
TCGA: ENSG00000141161
COSMIC: UNC45B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141161ENST00000268876Q8IWX7
ENSG00000141161ENST00000394570Q8IWX7
ENSG00000141161ENST00000591048Q8IWX7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
372954242023Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.0
372954242023Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B.0
332173082020Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores.21
332173082020Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores.21
254364182015Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone.9
254364182015Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone.9
245490502014The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract.21
245490502014The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract.21
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

UNC45B (unc-45 myosin chaperone B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75484/unc45b-(unc-45-myosin-chaperone-b)