Identity
HGNC
LOCATION
10p14
LOCUSID
ALIAS
HUPF2,RENT2,smg-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26019
MIM: 605529
HGNC: 17854
Ensembl: ENSG00000151461
Variants:
dbSNP: 26019
ClinVar: 26019
TCGA: ENSG00000151461
COSMIC: UPF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000151461 | ENST00000356352 | Q9HAU5 |
| ENSG00000151461 | ENST00000357604 | Q9HAU5 |
| ENSG00000151461 | ENST00000397053 | Q9HAU5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38056247 | 2024 | An alternative spliced UPF2 transcript in pancreatic inflammatory myofibroblastic tumors. | 0 |
| 38709891 | 2024 | UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. | 0 |
| 38056247 | 2024 | An alternative spliced UPF2 transcript in pancreatic inflammatory myofibroblastic tumors. | 0 |
| 38709891 | 2024 | UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. | 0 |
| 36456182 | 2023 | Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2. | 6 |
| 36456182 | 2023 | Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2. | 6 |
| 35640974 | 2022 | Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. | 6 |
| 35640974 | 2022 | Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. | 6 |
| 31585809 | 2019 | Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response. | 32 |
| 31699982 | 2019 | Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. | 19 |
| 31585809 | 2019 | Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response. | 32 |
| 31699982 | 2019 | Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. | 19 |
| 26740584 | 2016 | Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex. | 32 |
| 26740584 | 2016 | Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex. | 32 |
| 24173962 | 2014 | Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells. | 4 |
Citation
Dessen P
UPF2 (UPF2 regulator of nonsense mediated mRNA decay)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75496/upf2-(upf2-regulator-of-nonsense-mediated-mrna-decay)
