Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54532
MIM: 617431
HGNC: 29255
Ensembl: ENSG00000145390
Variants:
dbSNP: 54532
ClinVar: 54532
TCGA: ENSG00000145390
COSMIC: USP53
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000145390 | ENST00000274030 | Q70EK8 |
| ENSG00000145390 | ENST00000450251 | Q70EK8 |
| ENSG00000145390 | ENST00000507906 | H0Y8Q1 |
| ENSG00000145390 | ENST00000509769 | D6RF54 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34919659 | 2022 | USP53 activated by H3K27 acetylation regulates cell viability, apoptosis and metabolism in esophageal carcinoma via the AMPK signaling pathway. | 5 |
| 34919659 | 2022 | USP53 activated by H3K27 acetylation regulates cell viability, apoptosis and metabolism in esophageal carcinoma via the AMPK signaling pathway. | 5 |
| 32759993 | 2021 | New paradigms of USP53 disease: normal GGT cholestasis, BRIC, cholangiopathy, and responsiveness to rifampicin. | 12 |
| 33075013 | 2021 | Cholestasis Due to USP53 Deficiency. | 10 |
| 33664230 | 2021 | Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. | 15 |
| 33973730 | 2021 | Ubiquitin-specific peptidase 53 inhibits the occurrence and development of clear cell renal cell carcinoma through NF-κB pathway inactivation. | 8 |
| 32759993 | 2021 | New paradigms of USP53 disease: normal GGT cholestasis, BRIC, cholangiopathy, and responsiveness to rifampicin. | 12 |
| 33075013 | 2021 | Cholestasis Due to USP53 Deficiency. | 10 |
| 33664230 | 2021 | Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. | 15 |
| 33973730 | 2021 | Ubiquitin-specific peptidase 53 inhibits the occurrence and development of clear cell renal cell carcinoma through NF-κB pathway inactivation. | 8 |
| 32124521 | 2020 | Low-GGT intrahepatic cholestasis associated with biallelic USP53 variants: Clinical, histological and ultrastructural characterization. | 18 |
| 32508265 | 2020 | Knockdown of Ubiquitin-Specific Protease 53 Enhances the Radiosensitivity of Human Cervical Squamous Cell Carcinoma by Regulating DNA Damage-Binding Protein 2. | 8 |
| 32511815 | 2020 | USP53 promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through FKBP51-AKT1 signaling. | 16 |
| 32124521 | 2020 | Low-GGT intrahepatic cholestasis associated with biallelic USP53 variants: Clinical, histological and ultrastructural characterization. | 18 |
| 32508265 | 2020 | Knockdown of Ubiquitin-Specific Protease 53 Enhances the Radiosensitivity of Human Cervical Squamous Cell Carcinoma by Regulating DNA Damage-Binding Protein 2. | 8 |
Citation
Dessen P
USP53 (ubiquitin specific peptidase 53)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75569/chromosome-explorer/meetings/
