VPS29 (VPS29 retromer complex component)

2014-11-01  

Identity

HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
DC15,DC7,PEP11
FUSION GENES

Other Information

Locus ID:

NCBI: 51699
MIM: 606932
HGNC: 14340
Ensembl: ENSG00000111237

Variants:

dbSNP: 51699
ClinVar: 51699
TCGA: ENSG00000111237
COSMIC: VPS29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111237ENST00000360579Q9UBQ0
ENSG00000111237ENST00000360579A0A384MR19
ENSG00000111237ENST00000447578Q05DG7
ENSG00000111237ENST00000546588F8VXU5
ENSG00000111237ENST00000549578Q9UBQ0
ENSG00000111237ENST00000549970Q05DG7
ENSG00000111237ENST00000552130Q05DG7
ENSG00000111237ENST00000621131F8VXU5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379163252023Potential functions and causal associations of VPS29 in hepatocellular carcinoma: a bioinformatic and Mendelian randomization study.1
379163252023Potential functions and causal associations of VPS29 in hepatocellular carcinoma: a bioinformatic and Mendelian randomization study.1
327372862020Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis.33
330241122020Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.12
327372862020Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis.33
330241122020Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.12
269656912017Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.13
288920792017Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.147
291469122017Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.29
269656912017Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.13
288920792017Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.147
291469122017Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.29
254751422015Genetic variability of the retromer cargo recognition complex in parkinsonism.17
259371192015VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.18
254751422015Genetic variability of the retromer cargo recognition complex in parkinsonism.17

Citation

Dessen P

VPS29 (VPS29 retromer complex component)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75632/vps29-(vps29-retromer-complex-component)