Identity
HGNC
LOCATION
1q21.2
LOCUSID
ALIAS
H1,H1VPS45,SCN5,VPS45A,VPS45B,VPS54A,VSP45,VSP45A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11311
MIM: 610035
HGNC: 14579
Ensembl: ENSG00000136631
Variants:
dbSNP: 11311
ClinVar: 11311
TCGA: ENSG00000136631
COSMIC: VPS45
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33512427 | 2021 | Mammalian VPS45 orchestrates trafficking through the endosomal system. | 12 |
| 33512427 | 2021 | Mammalian VPS45 orchestrates trafficking through the endosomal system. | 12 |
| 31988382 | 2020 | FERARI is required for Rab11-dependent endocytic recycling. | 35 |
| 32590190 | 2020 | SPI1-induced upregulation of lncRNA SNHG6 promotes non-small cell lung cancer via miR-485-3p/VPS45 axis. | 21 |
| 31988382 | 2020 | FERARI is required for Rab11-dependent endocytic recycling. | 35 |
| 32590190 | 2020 | SPI1-induced upregulation of lncRNA SNHG6 promotes non-small cell lung cancer via miR-485-3p/VPS45 axis. | 21 |
| 26358756 | 2015 | Severe congenital neutropenia with neurological impairment due to a homozygous VPS45 p.E238K mutation: A case report suggesting a genotype-phenotype correlation. | 9 |
| 26358756 | 2015 | Severe congenital neutropenia with neurological impairment due to a homozygous VPS45 p.E238K mutation: A case report suggesting a genotype-phenotype correlation. | 9 |
| 23599270 | 2013 | The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy. | 28 |
| 23738510 | 2013 | A congenital neutrophil defect syndrome associated with mutations in VPS45. | 50 |
| 23599270 | 2013 | The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy. | 28 |
| 23738510 | 2013 | A congenital neutrophil defect syndrome associated with mutations in VPS45. | 50 |
| 19931244 | 2010 | Common and distinct roles for the binding partners Rabenosyn-5 and Vps45 in the regulation of endocytic trafficking in mammalian cells. | 27 |
| 19931244 | 2010 | Common and distinct roles for the binding partners Rabenosyn-5 and Vps45 in the regulation of endocytic trafficking in mammalian cells. | 27 |
Citation
Dessen P
VPS45 (vacuolar protein sorting 45 homolog)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75638/vps45-(vacuolar-protein-sorting-45-homolog)
