Identity
HGNC
LOCATION
6q24.1
LOCUSID
ALIAS
6orf55,C6orf55,DRG-1,DRG1,HSPC228,LIP5,My012,SBP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51534
MIM: 610902
HGNC: 20954
Ensembl: ENSG00000009844
Variants:
dbSNP: 51534
ClinVar: 51534
TCGA: ENSG00000009844
COSMIC: VTA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000009844 | ENST00000367621 | Q5TGM0 |
| ENSG00000009844 | ENST00000367630 | Q9NP79 |
| ENSG00000009844 | ENST00000452973 | Q9NP79 |
| ENSG00000009844 | ENST00000620996 | A0A087WY55 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38372114 | 2024 | High expression of VTA1 is an adverse prognostic factor in lung adenocarcinoma. | 1 |
| 38687820 | 2024 | The human AAA-ATPase VPS4A isoform and its co-factor VTA1 have a unique function in regulating mammalian cytokinesis abscission. | 0 |
| 38372114 | 2024 | High expression of VTA1 is an adverse prognostic factor in lung adenocarcinoma. | 1 |
| 38687820 | 2024 | The human AAA-ATPase VPS4A isoform and its co-factor VTA1 have a unique function in regulating mammalian cytokinesis abscission. | 0 |
| 31661793 | 2019 | Structural Insights into AQP2 Targeting to Multivesicular Bodies. | 8 |
| 31661793 | 2019 | Structural Insights into AQP2 Targeting to Multivesicular Bodies. | 8 |
| 28710278 | 2017 | Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5. | 15 |
| 28710278 | 2017 | Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5. | 15 |
| 25637630 | 2015 | A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5. | 21 |
| 25657007 | 2015 | Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains. | 26 |
| 25637630 | 2015 | A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5. | 21 |
| 25657007 | 2015 | Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains. | 26 |
| 25164817 | 2014 | Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis. | 13 |
| 25164817 | 2014 | Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis. | 13 |
| 23105106 | 2012 | Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. | 30 |
Citation
Dessen P
VTA1 (vesicle trafficking 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75657/submit-meetings/
