WBP4 (WW domain binding protein 4)

2014-11-01  

Identity

HGNC
LOCATION
13q14.11
LOCUSID
ALIAS
FBP21
FUSION GENES

Other Information

Locus ID:

NCBI: 11193
MIM: 604981
HGNC: 12739
Ensembl: ENSG00000120688

Variants:

dbSNP: 11193
ClinVar: 11193
TCGA: ENSG00000120688
COSMIC: WBP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120688ENST00000379487O75554

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
305588862019FBP21's C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase.2
305588862019FBP21's C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase.2
288382052017A new role for FBP21 as regulator of Brr2 helicase activity.15
288382052017A new role for FBP21 as regulator of Brr2 helicase activity.15
219179302011Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome.16
219179302011Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome.16
195927032009Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).30
195927032009Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).30

Citation

Dessen P

WBP4 (WW domain binding protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75688/wbp4-(ww-domain-binding-protein-4)