WDR24 (WD repeat domain 24)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf21,JFP7
FUSION GENES

Other Information

Locus ID:

NCBI: 84219
HGNC: 20852
Ensembl: ENSG00000127580

Variants:

dbSNP: 84219
ClinVar: 84219
TCGA: ENSG00000127580
COSMIC: WDR24

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127580ENST00000248142A0A499FJD3
ENSG00000127580ENST00000293883Q96S15
ENSG00000127580ENST00000647644A0A3B3ISA1

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
mTOR signaling pathwayKEGGhsa04150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369959372023CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.9
369959372023CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.9
319152522020The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.24
319152522020The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.24
271668232016The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.26
271668232016The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.26

Citation

Dessen P

WDR24 (WD repeat domain 24)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75703/wdr24-(wd-repeat-domain-24)