Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
NEDSBAS,WDR45L,WIPI-3,WIPI3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56270
MIM: 609226
HGNC: 25072
Ensembl: ENSG00000141580
Variants:
dbSNP: 56270
ClinVar: 56270
TCGA: ENSG00000141580
COSMIC: WDR45B
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Macroautophagy | REACTOME | R-HSA-1632852 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35962600 | 2022 | A homozygous variant of WDR45B results in global developmental delay: Additional case and literature review. | 1 |
| 35962600 | 2022 | A homozygous variant of WDR45B results in global developmental delay: Additional case and literature review. | 1 |
| 32483132 | 2020 | Multi-site-mediated entwining of the linear WIR-motif around WIPI β-propellers for autophagy. | 19 |
| 32483132 | 2020 | Multi-site-mediated entwining of the linear WIR-motif around WIPI β-propellers for autophagy. | 19 |
| 28503735 | 2018 | WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome. | 24 |
| 28503735 | 2018 | WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome. | 24 |
| 28561066 | 2017 | WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. | 101 |
| 28561066 | 2017 | WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. | 101 |
Citation
Dessen P
WDR45B (WD repeat domain 45B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75716/wdr45b-(wd-repeat-domain-45b)
