WDR7 (WD repeat domain 7)

2014-11-01  

Identity

HGNC
WDR7
LOCATION
18q21.31
LOCUSID
23335
ALIAS
TRAG
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23335
MIM: 613473
HGNC: 13490
Ensembl: ENSG00000091157

Variants:

dbSNP: 23335
ClinVar: 23335
TCGA: ENSG00000091157
COSMIC: WDR7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000091157ENST00000254442Q9Y4E6
ENSG00000091157ENST00000357574Q9Y4E6
ENSG00000091157ENST00000585669K7EMF3
ENSG00000091157ENST00000589935K7EPQ4
ENSG00000091157ENST00000591449K7EPY9
ENSG00000091157ENST00000593058K7EMB8
ENSG00000091157ENST00000615645A2RRE0

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA128406956fluorouracilChemicalVariantAnnotationnot associatedPD
PA445058Neoplasm MetastasisDiseaseVariantAnnotationnot associatedPD
PA448771capecitabineChemicalVariantAnnotationnot associatedPD

References

Pubmed IDYearTitleCitations
327503152020Evolution of a Human-Specific Tandem Repeat Associated with ALS.26
327503152020Evolution of a Human-Specific Tandem Repeat Associated with ALS.26
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94

Citation

Dessen P

WDR7 (WD repeat domain 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75727/wdr7-(wd-repeat-domain-7)