Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54663
MIM: 617947
HGNC: 25529
Ensembl: ENSG00000133316
Variants:
dbSNP: 54663
ClinVar: 54663
TCGA: ENSG00000133316
COSMIC: WDR74
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36701849 | 2023 | WDR74 rs11231247 contributes to the susceptibility and prognosis of non-small cell lung cancer. | 1 |
| 37331183 | 2023 | WDR74 serves as a novel therapeutic target by its oncogenic role in hepatocellular carcinoma. | 0 |
| 36701849 | 2023 | WDR74 rs11231247 contributes to the susceptibility and prognosis of non-small cell lung cancer. | 1 |
| 37331183 | 2023 | WDR74 serves as a novel therapeutic target by its oncogenic role in hepatocellular carcinoma. | 0 |
| 31838084 | 2020 | WDR74 induces nuclear β-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis. | 17 |
| 32005977 | 2020 | WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5-MDM2-p53 pathway. | 11 |
| 31838084 | 2020 | WDR74 induces nuclear β-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis. | 17 |
| 32005977 | 2020 | WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5-MDM2-p53 pathway. | 11 |
| 29107693 | 2018 | WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2. | 12 |
| 30594465 | 2018 | WDR74 functions as a novel coactivator in TGF-β signaling. | 4 |
| 29107693 | 2018 | WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2. | 12 |
| 30594465 | 2018 | WDR74 functions as a novel coactivator in TGF-β signaling. | 4 |
| 26456651 | 2015 | AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74. | 12 |
| 26456651 | 2015 | AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74. | 12 |
Citation
Dessen P
WDR74 (WD repeat domain 74)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75729/wdr74-(wd-repeat-domain-74)
