WDR82 (WD repeat domain 82)

2014-11-01  

Identity

HGNC
WDR82
LOCATION
3p21.2
LOCUSID
80335
ALIAS
MST107,MSTP107,PRO2730,PRO34047,SWD2,TMEM113,WDR82A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80335
MIM: 611059
HGNC: 28826
Ensembl: ENSG00000164091

Variants:

dbSNP: 80335
ClinVar: 80335
TCGA: ENSG00000164091
COSMIC: WDR82

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164091ENST00000296490Q6UXN9
ENSG00000164091ENST00000296490A0A024R333
ENSG00000164091ENST00000463624C9J355
ENSG00000164091ENST00000469000C9JBU3

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015

References

Pubmed IDYearTitleCitations
370300682023Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.1
370300682023Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.1
353252032022ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters.7
353252032022ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters.7
337674522021A first exon termination checkpoint preferentially suppresses extragenic transcription.19
337674522021A first exon termination checkpoint preferentially suppresses extragenic transcription.19
337674522021A first exon termination checkpoint preferentially suppresses extragenic transcription.19
337674522021A first exon termination checkpoint preferentially suppresses extragenic transcription.19
265195362015WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines.9
265195362015WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines.9
205160612010Identification and characterization of a novel human PP1 phosphatase complex.71
205160612010Identification and characterization of a novel human PP1 phosphatase complex.71
179983322008Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.114
188385382008Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.174
179983322008Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.114

Citation

Dessen P

WDR82 (WD repeat domain 82)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75733/wdr82-(wd-repeat-domain-82)