Identity
HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
WHAMM1,WHDC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 123720
MIM: 612393
HGNC: 30493
Ensembl: ENSG00000156232
Variants:
dbSNP: 123720
ClinVar: 123720
TCGA: ENSG00000156232
COSMIC: WHAMM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156232 | ENST00000286760 | Q8TF30 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Tight junction | KEGG | ko04530 |
| Tight junction | KEGG | hsa04530 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38598293 | 2024 | WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration. | 0 |
| 38598293 | 2024 | WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration. | 0 |
| 33036756 | 2021 | An actin-WHAMM interaction linking SETD2 and autophagy. | 5 |
| 33872315 | 2021 | The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis. | 9 |
| 33036756 | 2021 | An actin-WHAMM interaction linking SETD2 and autophagy. | 5 |
| 33872315 | 2021 | The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis. | 9 |
| 31420534 | 2019 | WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. | 33 |
| 31420534 | 2019 | WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. | 33 |
| 26096974 | 2015 | WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. | 71 |
| 26096974 | 2015 | WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. | 71 |
| 23027905 | 2012 | Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling. | 21 |
| 23087206 | 2012 | RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules. | 30 |
| 23027905 | 2012 | Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling. | 21 |
| 23087206 | 2012 | RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules. | 30 |
Citation
Dessen P
WHAMM (WASP homolog associated with actin, golgi membranes and microtubules)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75759/whamm-(wasp-homolog-associated-with-actin-golgi-membranes-and-microtubules)
