Identity
HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
APP3,ICP55,NPHPL1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 63929
MIM: 613553
HGNC: 28052
Ensembl: ENSG00000196236
Variants:
dbSNP: 63929
ClinVar: 63929
TCGA: ENSG00000196236
COSMIC: XPNPEP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196236 | ENST00000357137 | Q9NQH7 |
| ENSG00000196236 | ENST00000428799 | F2Z316 |
| ENSG00000196236 | ENST00000614001 | A0A087X0Z2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29383790 | 2018 | XPNPEP3 is a novel transcriptional target of canonical Wnt/β-catenin signaling. | 4 |
| 29383790 | 2018 | XPNPEP3 is a novel transcriptional target of canonical Wnt/β-catenin signaling. | 4 |
| 28476889 | 2017 | Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes. | 17 |
| 28476889 | 2017 | Structure of the human aminopeptidase XPNPEP3 and comparison of its in vitro activity with Icp55 orthologs: Insights into diverse cellular processes. | 17 |
| 25609706 | 2015 | Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2. | 14 |
| 25609706 | 2015 | Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2. | 14 |
| 21068128 | 2011 | Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy. | 72 |
| 21068128 | 2011 | Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy. | 72 |
| 20179356 | 2010 | Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. | 65 |
| 20179356 | 2010 | Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. | 65 |
Citation
Dessen P
XPNPEP3 (X-prolyl aminopeptidase 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75792/xpnpep3-(x-prolyl-aminopeptidase-3)
