YRDC (yrdC N6-threonylcarbamoyltransferase domain containing)

2014-11-01  

Identity

HGNC
YRDC
LOCATION
1p34.3
LOCUSID
79693
ALIAS
DRIP3,IRIP,SUA5

Other Information

Locus ID:

NCBI: 79693
MIM: 612276
HGNC: 28905
Ensembl: ENSG00000196449

Variants:

dbSNP: 79693
ClinVar: 79693
TCGA: ENSG00000196449
COSMIC: YRDC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196449ENST00000373044Q86U90

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
364354522023RNA Structural Dynamics Modulate EGFR-TKI Resistance Through Controlling YRDC Translation in NSCLC Cells.4
364354522023RNA Structural Dynamics Modulate EGFR-TKI Resistance Through Controlling YRDC Translation in NSCLC Cells.4
345454592021Biallelic variants in YRDC cause a developmental disorder with progeroid features.2
345454592021Biallelic variants in YRDC cause a developmental disorder with progeroid features.2
309785262019Modulation of YrdC promotes hepatocellular carcinoma progression via MEK/ERK signaling pathway.12
314816692019Defects in t(6)A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.40
309785262019Modulation of YrdC promotes hepatocellular carcinoma progression via MEK/ERK signaling pathway.12
314816692019Defects in t(6)A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.40
192792272009Ischemia-reperfusion-inducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter.2
192792272009Ischemia-reperfusion-inducible protein modulates cell sensitivity to anticancer drugs by regulating activity of efflux transporter.2
127307172003Isolation and identification of a novel cDNA that encodes human yrdC protein.8
127307172003Isolation and identification of a novel cDNA that encodes human yrdC protein.8

Citation

Dessen P

YRDC (yrdC N6-threonylcarbamoyltransferase domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75822/yrdc-(yrdc-n6-threonylcarbamoyltransferase-domain-containing)