YTHDF3 (YTH N6-methyladenosine RNA binding protein 3)

2014-11-01  

Identity

HGNC
LOCATION
8q12.3
LOCUSID
ALIAS
DF3
FUSION GENES

Other Information

Locus ID:

NCBI: 253943
MIM: 618669
HGNC: 26465
Ensembl: ENSG00000185728

Variants:

dbSNP: 253943
ClinVar: 253943
TCGA: ENSG00000185728
COSMIC: YTHDF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185728ENST00000517371S4R373
ENSG00000185728ENST00000539294Q7Z739
ENSG00000185728ENST00000612880A0A087WWB0
ENSG00000185728ENST00000613853A0A087X0U5
ENSG00000185728ENST00000615676A0A087X0C3
ENSG00000185728ENST00000617200A0A024R7W5
ENSG00000185728ENST00000617952A0A087WU40
ENSG00000185728ENST00000619337A0A087WU63
ENSG00000185728ENST00000621413A0A087WY31
ENSG00000185728ENST00000621820A0A087WY31
ENSG00000185728ENST00000621890A0A024R7W5
ENSG00000185728ENST00000621957A0A087X0Q1
ENSG00000185728ENST00000623280A0A024R7W5

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
382501522024The inhibition of YTHDF3/m(6)A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer.1
388219162024ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression.0
390547192024Knockdown of YAP1 Reduces YTHDF3 to Stabilize SMAD7 and thus Inhibit Bladder Cancer Stem Cell Stemness.0
382501522024The inhibition of YTHDF3/m(6)A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer.1
388219162024ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression.0
390547192024Knockdown of YAP1 Reduces YTHDF3 to Stabilize SMAD7 and thus Inhibit Bladder Cancer Stem Cell Stemness.0
361714552023N(6)-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.10
363806872023YTHDF3 mediates HNF1α regulation of cervical cancer radio-resistance by promoting RAD51D translation in an m6A-dependent manner.9
371490732023m(6)A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.1
374497892023m(6) A reader YTHDF3 triggers the progression of hepatocellular carcinoma through the YTHDF3/m(6) A-EGFR/STAT3 axis and EMT.1
380301882023YTHDF3 Modulates EGFR/ATK/ERK/p21 Signaling Axis to Promote Cancer Progression and Osimertinib Resistance of Glioblastoma Cells.1
361714552023N(6)-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability.10
363806872023YTHDF3 mediates HNF1α regulation of cervical cancer radio-resistance by promoting RAD51D translation in an m6A-dependent manner.9
371490732023m(6)A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.1
374497892023m(6) A reader YTHDF3 triggers the progression of hepatocellular carcinoma through the YTHDF3/m(6) A-EGFR/STAT3 axis and EMT.1

Citation

Dessen P

YTHDF3 (YTH N6-methyladenosine RNA binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75824