ZC3H14 (zinc finger CCCH-type containing 14)

2014-11-01  

Identity

HGNC
LOCATION
14q31.3
LOCUSID
ALIAS
MRT56,MSUT-2,NY-REN-37,SUT2,UKp68
FUSION GENES

Other Information

Locus ID:

NCBI: 79882
MIM: 613279
HGNC: 20509
Ensembl: ENSG00000100722

Variants:

dbSNP: 79882
ClinVar: 79882
TCGA: ENSG00000100722
COSMIC: ZC3H14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100722ENST00000251038Q6PJT7
ENSG00000100722ENST00000302216Q6PJT7
ENSG00000100722ENST00000318308Q6PJT7
ENSG00000100722ENST00000336693Q6PJT7
ENSG00000100722ENST00000393514Q6PJT7
ENSG00000100722ENST00000406216Q6PJT7
ENSG00000100722ENST00000553495G3V2X4
ENSG00000100722ENST00000554602G3V473
ENSG00000100722ENST00000555120G3V240
ENSG00000100722ENST00000555755Q6PJT7
ENSG00000100722ENST00000555792H0YJ51
ENSG00000100722ENST00000555799G3V3Y4
ENSG00000100722ENST00000555900G3V411
ENSG00000100722ENST00000556000H0YJA2
ENSG00000100722ENST00000556110H0YJ87
ENSG00000100722ENST00000556158G3V3R9
ENSG00000100722ENST00000556945G3V256
ENSG00000100722ENST00000557047A0A087WTC9
ENSG00000100722ENST00000557607G3V5I6
ENSG00000100722ENST00000557693G3V572
ENSG00000100722ENST00000557737G3V4R5
ENSG00000100722ENST00000649731A0A3B3IT62

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
329814222021AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.1
329814222021AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.1
303717402019Downregulation of ZC3H14 driven by chromosome 14q31 deletion promotes hepatocellular carcinoma progression by activating integrin signaling.6
303717402019Downregulation of ZC3H14 driven by chromosome 14q31 deletion promotes hepatocellular carcinoma progression by activating integrin signaling.6
275630652016The Polyadenosine RNA-binding Protein, Zinc Finger Cys3His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA.13
275630652016The Polyadenosine RNA-binding Protein, Zinc Finger Cys3His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA.13
246717642014A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.35
246717642014A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.35
213550462011MSUT2 is a determinant of susceptibility to tau neurotoxicity.37
217341512011Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans.44
213550462011MSUT2 is a determinant of susceptibility to tau neurotoxicity.37
217341512011Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans.44
206589872010The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?6
206589872010The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?6
193030452009Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein.33

Citation

Dessen P

ZC3H14 (zinc finger CCCH-type containing 14)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75881/zc3h14-(zinc-finger-ccch-type-containing-14)