ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16)

2014-11-01  

Identity

HGNC
ZDHHC16
LOCATION
10q24.1
LOCUSID
84287
ALIAS
APH2,DHHC-16
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84287
MIM: 616750
HGNC: 20714
Ensembl: ENSG00000171307

Variants:

dbSNP: 84287
ClinVar: 84287
TCGA: ENSG00000171307
COSMIC: ZDHHC16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171307ENST00000345745Q969W1
ENSG00000171307ENST00000352634Q969W1
ENSG00000171307ENST00000353979Q969W1
ENSG00000171307ENST00000370842Q969W1
ENSG00000171307ENST00000370846B1AMU0
ENSG00000171307ENST00000370854Q969W1
ENSG00000171307ENST00000393760Q969W1
ENSG00000171307ENST00000414567B1AMU5
ENSG00000171307ENST00000417044H0Y536
ENSG00000171307ENST00000420089H0Y6E9
ENSG00000171307ENST00000433086B1AMT9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384300442024METTL3-mediated m6A modification enhances ZDHHC16 expression in nonsmall- cell lung cancer patients, attenuating ferroptosis by suppressing CREB ubiquitination.0
384300442024METTL3-mediated m6A modification enhances ZDHHC16 expression in nonsmall- cell lung cancer patients, attenuating ferroptosis by suppressing CREB ubiquitination.0
351928902022SETD2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage.8
351928902022SETD2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage.8
288264752017Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade.64
288264752017Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade.64
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
171236472006Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1.4
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
171236472006Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1.4

Citation

Dessen P

ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75908/zdhhc16-(zinc-finger-dhhc-type-palmitoyltransferase-16)