Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
DHHC8,ZDHHCL1,ZNF378
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29801
MIM: 608784
HGNC: 18474
Ensembl: ENSG00000099904
Variants:
dbSNP: 29801
ClinVar: 29801
TCGA: ENSG00000099904
COSMIC: ZDHHC8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000099904 | ENST00000320602 | Q9ULC8 |
| ENSG00000099904 | ENST00000334554 | Q9ULC8 |
| ENSG00000099904 | ENST00000405930 | Q9ULC8 |
| ENSG00000099904 | ENST00000436518 | C9JVM2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38211651 | 2024 | AMPKα1-mediated ZDHHC8 phosphorylation promotes the palmitoylation of SLC7A11 to facilitate ferroptosis resistance in glioblastoma. | 3 |
| 38211651 | 2024 | AMPKα1-mediated ZDHHC8 phosphorylation promotes the palmitoylation of SLC7A11 to facilitate ferroptosis resistance in glioblastoma. | 3 |
| 28562378 | 2017 | Lack of association between COMT Val158Met and ZDHHC8 rs175174 polymorphisms and susceptibility to schizophrenia in a Brazilian population. | 0 |
| 28562378 | 2017 | Lack of association between COMT Val158Met and ZDHHC8 rs175174 polymorphisms and susceptibility to schizophrenia in a Brazilian population. | 0 |
| 23403413 | 2013 | ZDHHC8 gene may play a role in cortical volumes of patients with schizophrenia. | 11 |
| 23403413 | 2013 | ZDHHC8 gene may play a role in cortical volumes of patients with schizophrenia. | 11 |
| 22763378 | 2012 | Increased corpus callosum volume in children with chromosome 22q11.2 deletion syndrome is associated with neurocognitive deficits and genetic polymorphisms. | 7 |
| 22763378 | 2012 | Increased corpus callosum volume in children with chromosome 22q11.2 deletion syndrome is associated with neurocognitive deficits and genetic polymorphisms. | 7 |
| 19801377 | 2010 | Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. | 159 |
| 20468064 | 2010 | Association study of 182 candidate genes in anorexia nervosa. | 32 |
| 20468065 | 2010 | Association of ZDHHC8 polymorphisms with smooth pursuit eye movement abnormality. | 9 |
| 20468065 | 2010 | Association of ZDHHC8 polymorphisms with smooth pursuit eye movement abnormality. | 9 |
| 20661937 | 2010 | Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets. | 17 |
| 20661937 | 2010 | Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets. | 17 |
| 19801377 | 2010 | Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. | 159 |
Citation
Dessen P
ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75918/zdhhc8-(zinc-finger-dhhc-type-palmitoyltransferase-8)
