ZFYVE28 (zinc finger FYVE-type containing 28)

2014-11-01  

Identity

HGNC
ZFYVE28
LOCATION
4p16.3
LOCUSID
57732
ALIAS
LST2,LYST2,lst-2

Other Information

Locus ID:

NCBI: 57732
MIM: 614176
HGNC: 29334
Ensembl: ENSG00000159733

Variants:

dbSNP: 57732
ClinVar: 57732
TCGA: ENSG00000159733
COSMIC: ZFYVE28

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159733ENST00000290974Q9HCC9
ENSG00000159733ENST00000503000Q9HCC9
ENSG00000159733ENST00000508184D6RID3
ENSG00000159733ENST00000508471Q49AA1
ENSG00000159733ENST00000509171Q9HCC9
ENSG00000159733ENST00000511071Q9HCC9
ENSG00000159733ENST00000515169Q9HCC9
ENSG00000159733ENST00000515312Q9HCC9

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378845402023ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production.1
378845402023ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production.1
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
194603452009Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.14
194603452009Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.14

Citation

Dessen P

ZFYVE28 (zinc finger FYVE-type containing 28)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75955/zfyve28-(zinc-finger-fyve-type-containing-28)