ZNF407 (zinc finger protein 407)

2014-11-01  

Identity

HGNC
LOCATION
18q22.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 55628
MIM: 615894
HGNC: 19904
Ensembl: ENSG00000215421

Variants:

dbSNP: 55628
ClinVar: 55628
TCGA: ENSG00000215421
COSMIC: ZNF407

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000215421ENST00000299687Q9C0G0
ENSG00000215421ENST00000309902Q9C0G0
ENSG00000215421ENST00000577538Q9C0G0
ENSG00000215421ENST00000581829A0A087WV78
ENSG00000215421ENST00000582337Q9C0G0
ENSG00000215421ENST00000584235A0A087WYH1

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
327373942020Biallelic ZNF407 mutations in a neurodevelopmental disorder with ID, short stature and variable microcephaly, hypotonia, ocular anomalies and facial dysmorphism.3
327373942020Biallelic ZNF407 mutations in a neurodevelopmental disorder with ID, short stature and variable microcephaly, hypotonia, ocular anomalies and facial dysmorphism.3
283008332017PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.46
283008332017PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.46
231959522013Balanced translocation t(3;18)(p13;q22.3) and points mutation in the ZNF407 gene detected in patients with both moderate non-syndromic intellectual disability and autism.11
231959522013Balanced translocation t(3;18)(p13;q22.3) and points mutation in the ZNF407 gene detected in patients with both moderate non-syndromic intellectual disability and autism.11
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
196908902009Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.9
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
196908902009Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.9
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

ZNF407 (zinc finger protein 407)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76137/znf407-(zinc-finger-protein-407)