Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91752
MIM: 612282
HGNC: 21711
Ensembl: ENSG00000170396
Variants:
dbSNP: 91752
ClinVar: 91752
TCGA: ENSG00000170396
COSMIC: ZNF804A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170396 | ENST00000302277 | Q7Z570 |
| ENSG00000170396 | ENST00000613975 | A0A087X014 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447199 | Bipolar Disorder | Disease | ClinicalAnnotation | associated | PD | 29121268 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 21892778 | |
| PA450243 | lithium | Chemical | ClinicalAnnotation | associated | PD | 29121268 | |
| PA452233 | antipsychotics | Chemical | ClinicalAnnotation | associated | PD | 21892778 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38216065 | 2024 | Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism. | 0 |
| 38279611 | 2024 | Schizophrenia risk proteins ZNF804A and NT5C2 interact in cortical neurons. | 1 |
| 38702695 | 2024 | ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome. | 0 |
| 38216065 | 2024 | Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism. | 0 |
| 38279611 | 2024 | Schizophrenia risk proteins ZNF804A and NT5C2 interact in cortical neurons. | 1 |
| 38702695 | 2024 | ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome. | 0 |
| 33712377 | 2023 | Polymorphism in the ZNF804A Gene and Variation in D(1) and D(2)/D(3) Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study. | 2 |
| 34524581 | 2023 | Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci. | 3 |
| 35786202 | 2023 | Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis. | 3 |
| 33712377 | 2023 | Polymorphism in the ZNF804A Gene and Variation in D(1) and D(2)/D(3) Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study. | 2 |
| 34524581 | 2023 | Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci. | 3 |
| 35786202 | 2023 | Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis. | 3 |
| 31994908 | 2022 | The expression of zinc finger 804a (ZNF804a) and cyclin-dependent kinase 1 (CDK1) genes is related to the pathogenesis of rheumatoid arthritis. | 4 |
| 35447233 | 2022 | Genetic analysis of the ZNF804A gene in Mexican patients with schizophrenia, schizoaffective disorder and bipolar disorder. | 0 |
| 35728455 | 2022 | Study of a functional SNP rs13423388 in a novel enhancer element of schizophrenia-associated ZNF804A. | 0 |
Citation
Dessen P
ZNF804A (zinc finger protein 804A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/76416/znf804a-(zinc-finger-protein-804a)
