Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7783
MIM: 182888
HGNC: 13188
Ensembl: ENSG00000103310
Variants:
dbSNP: 7783
ClinVar: 7783
TCGA: ENSG00000103310
COSMIC: ZP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000103310 | ENST00000574002 | Q05996 |
| ENSG00000103310 | ENST00000574091 | Q05996 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Reproduction | REACTOME | R-HSA-1474165 |
| Fertilization | REACTOME | R-HSA-1187000 |
| Interaction With The Zona Pellucida | REACTOME | R-HSA-1300644 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38490181 | 2024 | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. | 0 |
| 38490181 | 2024 | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. | 0 |
| 36931917 | 2023 | Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida. | 4 |
| 36931917 | 2023 | Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida. | 4 |
| 35211729 | 2022 | Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice. | 6 |
| 35366744 | 2022 | Novel mutations in ZP2 and ZP3 cause female infertility in three patients. | 2 |
| 35595959 | 2022 | Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility. | 4 |
| 35211729 | 2022 | Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice. | 6 |
| 35366744 | 2022 | Novel mutations in ZP2 and ZP3 cause female infertility in three patients. | 2 |
| 35595959 | 2022 | Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility. | 4 |
| 33604805 | 2021 | A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility. | 7 |
| 33604805 | 2021 | A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility. | 7 |
| 32569527 | 2020 | Zona Pellucida Proteins, Fibrils, and Matrix. | 24 |
| 32829425 | 2020 | Novel mutations in ZP1 and ZP2 cause primary infertility due to empty follicle syndrome and abnormal zona pellucida. | 15 |
| 32569527 | 2020 | Zona Pellucida Proteins, Fibrils, and Matrix. | 24 |
Citation
Dessen P
ZP2 (zona pellucida glycoprotein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/76476/zp2-(zona-pellucida-glycoprotein-2)
