ZPBP2 (zona pellucida binding protein 2)

2014-11-01 Affiliation

Identity

HGNC

ZPBP2

LOCATION

17q21.1

LOCUSID

124626

ALIAS

ZPBPL

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 124626
MIM: 608499
HGNC: 20678
Ensembl: ENSG00000186075

Variants:

dbSNP: 124626
ClinVar: 124626
TCGA: ENSG00000186075
COSMIC: ZPBP2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000186075	ENST00000348931	Q6X784
ENSG00000186075	ENST00000377940	Q6X784
ENSG00000186075	ENST00000583811	J3KSF6
ENSG00000186075	ENST00000584588	J3KRM0

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33507524	2021	The Germ Cell-Specific Markers ZPBP2 and PGK2 in Testicular Biopsies Can Predict the Presence as well as the Quality of Sperm in Non-obstructive Azoospermia Patients.	5
33507524	2021	The Germ Cell-Specific Markers ZPBP2 and PGK2 in Testicular Biopsies Can Predict the Presence as well as the Quality of Sperm in Non-obstructive Azoospermia Patients.	5
31560728	2019	Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock.	2
31560728	2019	Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock.	2
28241063	2017	Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells.	19
28241063	2017	Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells.	19
26671913	2016	Local genotype influences DNA methylation at two asthma-associated regions, 5q31 and 17q21, in a founder effect population.	10
26671913	2016	Local genotype influences DNA methylation at two asthma-associated regions, 5q31 and 17q21, in a founder effect population.	10
25620289	2015	The allele T of rs10852936 confers risk for early-onset psoriasis.	2
25620289	2015	The allele T of rs10852936 confers risk for early-onset psoriasis.	2
22271045	2012	Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines.	29
22464253	2012	Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.	87
22271045	2012	Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines.	29
22464253	2012	Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.	87
19732864	2009	Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.	148

Citation

Dessen P

ZPBP2 (zona pellucida binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76480/zpbp2-(zona-pellucida-binding-protein-2)