ZSWIM8 (zinc finger SWIM-type containing 8)

2014-11-01  

Identity

HGNC
ZSWIM8
LOCATION
10q22.2
LOCUSID
23053
ALIAS
KIAA0913
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23053
HGNC: 23528
Ensembl: ENSG00000214655

Variants:

dbSNP: 23053
ClinVar: 23053
TCGA: ENSG00000214655
COSMIC: ZSWIM8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214655ENST00000398706A7E2V4
ENSG00000214655ENST00000412198H7C453
ENSG00000214655ENST00000433366H7BZ52
ENSG00000214655ENST00000466354S4R3S6
ENSG00000214655ENST00000492395H0YCW2
ENSG00000214655ENST00000603114S4R393
ENSG00000214655ENST00000603187S4R3U7
ENSG00000214655ENST00000604524S4R3H3
ENSG00000214655ENST00000604729S4R410
ENSG00000214655ENST00000604754S4R3B3
ENSG00000214655ENST00000605216A7E2V4

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359408472022The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization.4
359408472022The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization.4
346867002021ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation.5
346867002021ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation.5
331842342020A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming.91
331842372020The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation.97
331842342020A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming.91
331842372020The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation.97
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

ZSWIM8 (zinc finger SWIM-type containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76510/cancer-prone-explorer/meetings/humanGenome