ZWILCH (zwilch kinetochore protein)

2014-11-01  

Identity

HGNC
ZWILCH
LOCATION
15q22.31
LOCUSID
55055
ALIAS
KNTC1AP,hZwilch
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55055
MIM: 609984
HGNC: 25468
Ensembl: ENSG00000174442

Variants:

dbSNP: 55055
ClinVar: 55055
TCGA: ENSG00000174442
COSMIC: ZWILCH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174442ENST00000307897Q9H900
ENSG00000174442ENST00000446801Q9H900
ENSG00000174442ENST00000535141Q9H900
ENSG00000174442ENST00000564179H3BSG1
ENSG00000174442ENST00000565627Q9H900
ENSG00000174442ENST00000567816H3BQ07
ENSG00000174442ENST00000569489H3BPI7
ENSG00000174442ENST00000613446Q9H900

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813

References

Pubmed IDYearTitleCitations
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.14
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.14
190080952009Single nucleotide polymorphisms in chromosomal instability genes and risk and clinical outcome of breast cancer: a Swedish prospective case-control study.20
190080952009Single nucleotide polymorphisms in chromosomal instability genes and risk and clinical outcome of breast cancer: a Swedish prospective case-control study.20
126865952003Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.54
126865952003Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.54

Citation

Dessen P

ZWILCH (zwilch kinetochore protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76513/zwilch-(zwilch-kinetochore-protein)