BCCIP (BRCA2 and CDKN1A interacting protein)

2003-02-01  

Identity

HGNC
LOCATION
10q26.2
LOCUSID
ALIAS
TOK-1,TOK1
FUSION GENES

Other Information

Locus ID:

NCBI: 56647
MIM: 611883
HGNC: 978
Ensembl: ENSG00000107949

Variants:

dbSNP: 56647
ClinVar: 56647
TCGA: ENSG00000107949
COSMIC: BCCIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107949ENST00000278100Q9P287
ENSG00000107949ENST00000299130Q9P287
ENSG00000107949ENST00000368759Q9P287

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

References

Pubmed IDYearTitleCitations
383428122024Expression and Significance of BCCIP and Glutathione Peroxidase 4 in Clear Cell Renal Cell Carcinoma.0
383428122024Expression and Significance of BCCIP and Glutathione Peroxidase 4 in Clear Cell Renal Cell Carcinoma.0
334527182021Structure of human BCCIP and implications for binding and modification of partner proteins.2
342974842021Overexpression of BCCIP predicts an unfavorable prognosis and promotes the proliferation and migration of lung adenocarcinoma.5
334527182021Structure of human BCCIP and implications for binding and modification of partner proteins.2
342974842021Overexpression of BCCIP predicts an unfavorable prognosis and promotes the proliferation and migration of lung adenocarcinoma.5
327366932020BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.6
332457662020BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis.9
327366932020BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma.6
332457662020BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis.9
299322762018BCCIP binds to and activates its promoter in a YY1-dependent fashion in HCT116 cells.4
299322762018BCCIP binds to and activates its promoter in a YY1-dependent fashion in HCT116 cells.4
276946222017The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing.13
279954082017High Expression of BCCIP β Can Promote Proliferation of Esophageal Squamous Cell Carcinoma.4
283943422017Regulation of spindle integrity and mitotic fidelity by BCCIP.14

Citation

Dessen P

BCCIP (BRCA2 and CDKN1A interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/768/bccip-(brca2-and-cdkn1a-interacting-protein)