PTPN20 (protein tyrosine phosphatase non-receptor type 20)

2015-06-01  

Identity

HGNC
PTPN20
LOCATION
10q11.22
LOCUSID
26095
ALIAS
CT126,PTPN20A,PTPN20B,bA142I17.1,bA42B19.1

Other Information

Locus ID:

NCBI: 26095
MIM: 610631
HGNC: 23423
Ensembl: ENSG00000204179

Variants:

dbSNP: 26095
ClinVar: 26095
TCGA: ENSG00000204179
COSMIC: PTPN20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204179ENST00000374218Q4JDL3
ENSG00000204179ENST00000374339Q4JDL3
ENSG00000204179ENST00000374342Q4JDK3
ENSG00000204179ENST00000374346Q4JDL3
ENSG00000204179ENST00000395721Q4JDL3
ENSG00000204179ENST00000395722Q4JDK3
ENSG00000204179ENST00000395725Q4JDL3
ENSG00000204179ENST00000395727Q4JDL3
ENSG00000204179ENST00000417004Q5T1G4
ENSG00000204179ENST00000437863A0A0A0MSU6
ENSG00000204179ENST00000502254Q4JDL3
ENSG00000204179ENST00000502705Q4JDL3
ENSG00000204179ENST00000503851Q4JDL3
ENSG00000204179ENST00000505814Q4JDL3
ENSG00000204179ENST00000506080Q4JDL3
ENSG00000204179ENST00000506881D6RC68
ENSG00000204179ENST00000508357D6RF36
ENSG00000204179ENST00000508602Q4JDL3
ENSG00000204179ENST00000508715Q4JDK3
ENSG00000204179ENST00000509599Q4JDL3
ENSG00000204179ENST00000509774Q4JDL3
ENSG00000204179ENST00000509900Q4JDL3
ENSG00000204179ENST00000510335Q4JDL3
ENSG00000204179ENST00000511769Q4JDL3
ENSG00000204179ENST00000513156Q4JDL3
ENSG00000204179ENST00000513159Q4JDK3
ENSG00000204179ENST00000513266Q4JDL3
ENSG00000204179ENST00000513756Q4JDK3

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373595102023Identification of PTPN20 as an innate immunity-related gene in gastric cancer with Helicobacter pylori infection.1
373595102023Identification of PTPN20 as an innate immunity-related gene in gastric cancer with Helicobacter pylori infection.1
157903112005Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization.7
157903112005Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization.7

Citation

Dessen P

PTPN20 (protein tyrosine phosphatase non-receptor type 20)

Atlas Genet Cytogenet Oncol Haematol. 2015-06-01

Online version: http://atlasgeneticsoncology.org/gene/77515/ptpn20-(protein-tyrosine-phosphatase-non-receptor-type-20)