SNU13 (small nuclear ribonucleoprotein 13)

2015-09-01 Affiliation

Identity

HGNC

SNU13

LOCATION

22q13.2

LOCUSID

4809

ALIAS

15.5K,FA-1,FA1,NHP2L1,NHPX,OTK27,SNRNP15-5,SPAG12,SSFA1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4809
MIM: 601304
HGNC: 7819
Ensembl: ENSG00000100138

Variants:

dbSNP: 4809
ClinVar: 4809
TCGA: ENSG00000100138
COSMIC: SNU13

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000100138	ENST00000215956	P55769
ENSG00000100138	ENST00000215956	Q6FHM6
ENSG00000100138	ENST00000401959	P55769
ENSG00000100138	ENST00000401959	Q6FHM6
ENSG00000100138	ENST00000402458	B1AHD1
ENSG00000100138	ENST00000463675	A0A3B3IRU2
ENSG00000100138	ENST00000469028	A0A3B3ISH1
ENSG00000100138	ENST00000469522	A0A3B3ISH9
ENSG00000100138	ENST00000648350	A0A3B3IUA2
ENSG00000100138	ENST00000648674	P55769
ENSG00000100138	ENST00000648674	Q6FHM6
ENSG00000100138	ENST00000649479	A0A3B3IRU2
ENSG00000100138	ENST00000649722	A0A3B3ISK4

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Spliceosome	KEGG	ko03040
Spliceosome	KEGG	hsa03040
Ribosome biogenesis in eukaryotes	KEGG	ko03008
Ribosome biogenesis in eukaryotes	KEGG	hsa03008
Spliceosome, U4/U6.U5 tri-snRNP	KEGG	hsa_M00354
Spliceosome, U4/U6.U5 tri-snRNP	KEGG	M00354
Gene Expression	REACTOME	R-HSA-74160
Processing of Capped Intron-Containing Pre-mRNA	REACTOME	R-HSA-72203
mRNA Splicing	REACTOME	R-HSA-72172
mRNA Splicing - Major Pathway	REACTOME	R-HSA-72163
mRNA Splicing - Minor Pathway	REACTOME	R-HSA-72165
rRNA processing	REACTOME	R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol	REACTOME	R-HSA-6791226
rRNA modification in the nucleus and cytosol	REACTOME	R-HSA-6790901
rRNA processing in the nucleus and cytosol	REACTOME	R-HSA-8868773

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
27594683	2016	Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species.	12
27594683	2016	Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species.	12
19620283	2009	Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis.	47
19620283	2009	Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis.	47
18044964	2007	Functional implications for a prototypical K-turn binding protein from structural and dynamical studies of 15.5K.	4
18044964	2007	Functional implications for a prototypical K-turn binding protein from structural and dynamical studies of 15.5K.	4
12011111	2002	In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles.	19
12203836	2002	Molecular cloning and sequencing of cDNA encoding for human FA-1 antigen.	6
12417735	2002	Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP.	109
12011111	2002	In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles.	19
12203836	2002	Molecular cloning and sequencing of cDNA encoding for human FA-1 antigen.	6
12417735	2002	Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP.	109

Citation

Dessen P

SNU13 (small nuclear ribonucleoprotein 13)

Atlas Genet Cytogenet Oncol Haematol. 2015-09-01

Online version: http://atlasgeneticsoncology.org/gene/77775/snu13-(small-nuclear-ribonucleoprotein-13)