PPP4R3B (protein phosphatase 4 regulatory subunit 3B)

2015-09-01  

Identity

HGNC
PPP4R3B
LOCATION
2p16.1
LOCUSID
57223
ALIAS
FLFL2,PP4R3B,PSY2,SMEK2,smk1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57223
MIM: 610352
HGNC: 29267
Ensembl: ENSG00000275052

Variants:

dbSNP: 57223
ClinVar: 57223
TCGA: ENSG00000275052
COSMIC: PPP4R3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000275052ENST00000611717Q5MIZ7
ENSG00000275052ENST00000616288Q5MIZ7
ENSG00000275052ENST00000616407Q5MIZ7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glucagon signaling pathwayKEGGhsa04922
Glucagon signaling pathwayKEGGko04922

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
186140452008A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.124
186140452008A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.124

Citation

Dessen P

PPP4R3B (protein phosphatase 4 regulatory subunit 3B)

Atlas Genet Cytogenet Oncol Haematol. 2015-09-01

Online version: http://atlasgeneticsoncology.org/gene/77776/ppp4r3b-(protein-phosphatase-4-regulatory-subunit-3b)