Identity
HGNC
LOCATION
11q13.2
LOCUSID
ALIAS
CGI-85,CGI85,MRD51,SUV420H1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51111
MIM: 610881
HGNC: 24283
Ensembl: ENSG00000110066
Variants:
dbSNP: 51111
ClinVar: 51111
TCGA: ENSG00000110066
COSMIC: KMT5B
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38082550 | 2024 | Histone methyltransferase SUV420H1/KMT5B contributes to poor prognosis in hepatocellular carcinoma. | 1 |
| 38082550 | 2024 | Histone methyltransferase SUV420H1/KMT5B contributes to poor prognosis in hepatocellular carcinoma. | 1 |
| 36897941 | 2023 | Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice. | 3 |
| 37595555 | 2023 | Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. | 1 |
| 36897941 | 2023 | Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice. | 3 |
| 37595555 | 2023 | Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. | 1 |
| 35331928 | 2022 | Loss-of-function of KMT5B leads to neurodevelopmental disorder and impairs neuronal development and neurogenesis. | 7 |
| 35331928 | 2022 | Loss-of-function of KMT5B leads to neurodevelopmental disorder and impairs neuronal development and neurogenesis. | 7 |
| 34247492 | 2021 | Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. | 9 |
| 34716350 | 2021 | Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. | 13 |
| 34247492 | 2021 | Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. | 9 |
| 34716350 | 2021 | Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. | 13 |
| 33028632 | 2020 | Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells. | 5 |
| 33028632 | 2020 | Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells. | 5 |
| 31255706 | 2019 | Somatic Cancer Mutations in the SUV420H1 Protein Lysine Methyltransferase Modulate Its Catalytic Activity. | 7 |
Citation
Dessen P
KMT5B (lysine methyltransferase 5B)
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/gene/77843/kmt5b-(lysine-methyltransferase-5b)
