PLPPR4 (phospholipid phosphatase related 4)

2016-01-01  

Identity

HGNC
LOCATION
1p21.3
LOCUSID
ALIAS
LPPR4,LPR4,PHP1,PRG-1,PRG1
FUSION GENES

Other Information

Locus ID:

NCBI: 9890
MIM: 607813
HGNC: 23496
Ensembl: ENSG00000117600

Variants:

dbSNP: 9890
ClinVar: 9890
TCGA: ENSG00000117600
COSMIC: PLPPR4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117600ENST00000370184W4VSQ3
ENSG00000117600ENST00000370185Q7Z2D5
ENSG00000117600ENST00000457765Q7Z2D5

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Lysosphingolipid and LPA receptorsREACTOMER-HSA-419408

References

Pubmed IDYearTitleCitations
375508842023PLPPR4 haploinsufficiency causes neurodevelopmental disorders by disrupting synaptic plasticity via mTOR signalling.3
375508842023PLPPR4 haploinsufficiency causes neurodevelopmental disorders by disrupting synaptic plasticity via mTOR signalling.3
266719892016Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP.25
266719892016Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP.25
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

PLPPR4 (phospholipid phosphatase related 4)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/77955/plppr4-(phospholipid-phosphatase-related-4)