Identity
HGNC
LOCATION
3q29
LOCUSID
ALIAS
KIAA0226,RUBICON,SCAR15
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9711
MIM: 613516
HGNC: 28991
Ensembl: ENSG00000145016
Variants:
dbSNP: 9711
ClinVar: 9711
TCGA: ENSG00000145016
COSMIC: RUBCN
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Autophagy - animal | KEGG | ko04140 |
| Autophagy - animal | KEGG | hsa04140 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38728007 | 2024 | A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy. | 1 |
| 38728007 | 2024 | A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy. | 1 |
| 34932879 | 2022 | Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC. | 3 |
| 35740989 | 2022 | Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease. | 2 |
| 34932879 | 2022 | Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC. | 3 |
| 35740989 | 2022 | Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease. | 2 |
| 32165681 | 2020 | Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. | 6 |
| 32632011 | 2020 | Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex. | 17 |
| 32943718 | 2020 | Hepatitis C virus enhances Rubicon expression, leading to autophagy inhibition and intracellular innate immune activation. | 10 |
| 32165681 | 2020 | Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. | 6 |
| 32632011 | 2020 | Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex. | 17 |
| 32943718 | 2020 | Hepatitis C virus enhances Rubicon expression, leading to autophagy inhibition and intracellular innate immune activation. | 10 |
| 31752345 | 2019 | HUNK Phosphorylates Rubicon to Support Autophagy. | 7 |
| 31752345 | 2019 | HUNK Phosphorylates Rubicon to Support Autophagy. | 7 |
| 29215797 | 2018 | Rubicon: LC3-associated phagocytosis and beyond. | 53 |
Citation
Dessen P
RUBCN (rubicon autophagy regulator)
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/gene/77965/rubcn-(rubicon-autophagy-regulator)
