Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9868
MIM: 606081
HGNC: 11985
Ensembl: ENSG00000154174
Variants:
dbSNP: 9868
ClinVar: 9868
TCGA: ENSG00000154174
COSMIC: TOMM70
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154174 | ENST00000284320 | O94826 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37682539 | 2023 | The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis. | 1 |
| 37682539 | 2023 | The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis. | 1 |
| 35025629 | 2022 | Mitochondria shed their outer membrane in response to infection-induced stress. | 31 |
| 35025629 | 2022 | Mitochondria shed their outer membrane in response to infection-induced stress. | 31 |
| 33990585 | 2021 | Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions. | 63 |
| 34228876 | 2021 | Relation between ORF8a and the mitochondrial protein TOM70 in SARS-CoV-2 infection. | 0 |
| 34502139 | 2021 | Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90. | 17 |
| 33990585 | 2021 | Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions. | 63 |
| 34228876 | 2021 | Relation between ORF8a and the mitochondrial protein TOM70 in SARS-CoV-2 infection. | 0 |
| 34502139 | 2021 | Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90. | 17 |
| 31907385 | 2020 | Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay. | 18 |
| 32356556 | 2020 | De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment. | 20 |
| 32728199 | 2020 | SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70. | 211 |
| 31907385 | 2020 | Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay. | 18 |
| 32356556 | 2020 | De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment. | 20 |
Citation
Dessen P
TOMM70 (translocase of outer mitochondrial membrane 70)
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/gene/78309/case-report-explorer/gene-explorer/
