SGO2 (shugoshin 2)

2001-01-01  

Identity

HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
SGOL2,TRIPIN

Other Information

Locus ID:

NCBI: 151246
MIM: 612425
HGNC: 30812
Ensembl: ENSG00000163535

Variants:

dbSNP: 151246
ClinVar: 151246
TCGA: ENSG00000163535
COSMIC: SGO2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163535ENST00000357799Q562F6
ENSG00000163535ENST00000409203Q562F6
ENSG00000163535ENST00000418045C9JW92

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365660182022SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination.1
365660182022SGOL2 promotes prostate cancer progression by inhibiting RAB1A ubiquitination.1
342002612021High SGO2 Expression Predicts Poor Overall Survival: A Potential Therapeutic Target for Hepatocellular Carcinoma.2
345357052021Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas.6
342002612021High SGO2 Expression Predicts Poor Overall Survival: A Potential Therapeutic Target for Hepatocellular Carcinoma.2
345357052021Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas.6
323220602020Securin-independent regulation of separase by checkpoint-induced shugoshin-MAD2.21
323220602020Securin-independent regulation of separase by checkpoint-induced shugoshin-MAD2.21
315271462019Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere.12
315271462019Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere.12
276299232017Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome.13
287812332017Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis.16
276299232017Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome.13
287812332017Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis.16
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.25

Citation

Dessen P

SGO2 (shugoshin 2)

Atlas Genet Cytogenet Oncol Haematol. 2001-01-01

Online version: http://atlasgeneticsoncology.org/gene/78438/sgo2-(shugoshin-2)