Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
MAD7,MXD7,TCFL4,TF4,bHLHd13
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6945
MIM: 602976
HGNC: 11645
Ensembl: ENSG00000108788
Variants:
dbSNP: 6945
ClinVar: 6945
TCGA: ENSG00000108788
COSMIC: MLX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108788 | ENST00000246912 | Q9UH92 |
| ENSG00000108788 | ENST00000346833 | Q9UH92 |
| ENSG00000108788 | ENST00000435881 | Q9UH92 |
| ENSG00000108788 | ENST00000591024 | K7EID0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37088121 | 2023 | MLX plays a key role in lipid and glucose metabolism in humans: Evidence from in vitro and in vivo studies. | 1 |
| 37088121 | 2023 | MLX plays a key role in lipid and glucose metabolism in humans: Evidence from in vitro and in vivo studies. | 1 |
| 31919096 | 2020 | The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells. | 8 |
| 31919096 | 2020 | The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells. | 8 |
| 30354298 | 2018 | Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis. | 8 |
| 30354298 | 2018 | Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis. | 8 |
| 24857747 | 2015 | Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis. | 67 |
| 25640402 | 2015 | Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis. | 116 |
| 24857747 | 2015 | Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis. | 67 |
| 25640402 | 2015 | Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis. | 116 |
| 18458340 | 2008 | Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. | 151 |
| 18458340 | 2008 | Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. | 151 |
| 16782875 | 2006 | MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. | 68 |
| 16782875 | 2006 | MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. | 68 |
| 15664996 | 2005 | Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes. | 80 |
Citation
Dessen P
MLX (MAX dimerization protein MLX)
Atlas Genet Cytogenet Oncol Haematol. 2001-01-01
Online version: http://atlasgeneticsoncology.org/gene/78577/mlx-(max-dimerization-protein-mlx)
